PARD3 anticorps (AA 1306-1356)

N° du produit ABIN7453156

Cet anticorps Lapin Polyclonal détecte spécifiquement PARD3 dans WB. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour PARD3 anticorps (AA 1306-1356) (ABIN7453156)

Antigène: PARD3 (Par-3 Partitioning Defective 3 Homolog (PARD3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PARD3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PARD3 anticorps

Épitope: AA 1306-1356

Fonction: Rabbit anti-PARD3 Antibody, Affinity Purified

Homologie: Rat

Purification: Affinity Purified

Immunogène: Between AA 1306 and 1356

Isotype: IgG

Information d'application

Indications d'application:

IP: Not recommended

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur PARD3

Antigène: PARD3 (Par-3 Partitioning Defective 3 Homolog (PARD3))

Autre désignation: PARD3

Sujet: Background: Partitioning defective 3 homolog (Par3) is an adapter protein involved in asymmetrical cell division and cell polarization processes. It seems to play a central role in the formation of epithelial tight junctions and targets the phosphatase PTEN to cell junctions (By similarity). Par3 association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Par3 is required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons [taken from the Universal Protein Resource (UniProt) Q8TEW0].

ID gène: 56288

NCBI Accession: NP_062565

UniProt: Q8TEW0

Pathways: Cell-Cell Junction Organization